The Patriots will be without standout middle linebacker Jerod Mayo for likely at least the next six weeks due to a MCL sprain of his right knee.  Mayo only made 1 tackle against the Bills before he was injured.  Mayo was the Defensive Rookie of the Year in the NFL last season.  He played in all 16 games for the Patriots last season and he had 128 tackles, defensed 4 passes and he forced 1 fumble.  The Patriots will miss Mayo big time as he was the QB of the defense.  He will be replaced by 23-year old linebacker Gary Guyton.  Guyton had 4 tackles in the season opener against the Bills.  He played in 15 games as a rookie last season for the Patriots in which he made 34 tackles and defensed 3 passes.  Look for Guyton to do a good job for the Patriots while Mayo is out of action.